Figure 2. Fly-DPI offers two data pools for users to search against: one is the high-confidence dataset defined by Giot et al., 2003; and the other is the complete interactions contained in fly-DPI (1). Accepts search queries either by either ORF names, locus, RNA transcripts, FlyBase gene indexes, GO id, KEGG metabolisms, ec numbers or full-text search with keywords (2). Result listing order can be set by orf, locus, or transcript (3). Users can choose a specific chromosome for search (4). Desired GO category, either biological process, cellular component, molecular function or all of above, can be set at 5, in fig 2 as a filtering option. Options are available in the pull-down menu. Gene expression data from Unigene (NCBI) are incorporated to indicate where and which stage a protein is expressed. Currently, available options are: adult testes, brain, embryo, head, head-brain and sensory organ, ovary, salivary gland, tesis, whole body, whole embroy (6). Finally, there are options in the output format allowing users keeping all or only the necessary information in the result table (7), followed by a click on the "search" button. Top

Figure 3. Search results are listed in a table like fig 3. To view the interaction map of a target protein, simply select a probability threshold from the pull-down menu (1). Results can be downloaded in a excel format as well (2). View the interaction map.

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